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1

Regulatory T cells inhibit Fas ligand-induced innate and adaptive tumour immunity

Anna Katharina Simon, Emma Jones, Hannah Richards, Kate Wright, Gareth Betts, Andrew Godkin, Gavin Screaton, Awen Gallimore

Journal:

European Journal of Immunology

Year:

2007

Language:

english

File:

PDF, 383 KB

english, 2007

2

Home Sweet Home: The Tumor Microenvironment as a Haven for Regulatory T Cells

Ondondo, Beatrice, Jones, Emma, Godkin, Andrew, Gallimore, Awen

Journal:

Frontiers in Immunology

Year:

2013

Language:

english

File:

PDF, 648 KB

english, 2013

3

Monitoring regulatory T cells in clinical samples: consensus on an essential marker set and gating strategy for regulatory T cell analysis by flow cytometry

Santegoets, Saskia J. A. M., Dijkgraaf, Eveline M., Battaglia, Alessandra, Beckhove, Philipp, Britten, Cedrik M., Gallimore, Awen, Godkin, Andrew, Gouttefangeas, Cecile, de Gruijl, Tanja D., Koenen, H

Journal:

Cancer Immunology, Immunotherapy

Year:

2015

Language:

english

File:

PDF, 1.77 MB

english, 2015

4

A protective cytotoxic T cell response to a subdominant epitope is influenced by the stability of the MHC class I/peptide complex and the overall spectrum of viral peptides generated within infected cells

Awen Gallimore, Joachim Hombach, Tilman Dumrese, Hans-Georg Rammensee, Rolf M. Zinkernagel, Hans Hengartner

Journal:

European Journal of Immunology

Year:

1998

Language:

english

File:

PDF, 169 KB

english, 1998

5

Effect of epitope flanking residues on the presentation of N-terminal cytotoxic T lymphocyte epitopes

Uzi Gileadi, Awen Gallimore, Pierre Van der Bruggen, Vincenzo Cerundolo

Journal:

European Journal of Immunology

Year:

1999

Language:

english

File:

PDF, 158 KB

english, 1999

6

Functionally distinct CD8+ memory T cell subsets in persistent EBV infection are differentiated by migratory receptor expression

Lynda Tussey, Sue Speller, Awen Gallimore, Rupert Vessey

Journal:

European Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 163 KB

english, 2000

7

MHC class I-restricted killing of neurons by virus-specific CD8+ T lymphocytes is effected through the Fas/FasL, but not the perforin pathway

Isabelle M. Medana, Awen Gallimore, Annette Oxenius, Marianne M.A. Martinic, Hartmut Wekerle, Harald Neumann

Journal:

European Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 354 KB

english, 2000

8

Normal pathogen-specific immune responses mounted by CTLA-4-deficient T cells: a paradigm reconsidered

Martin F. Bachmann, Awen Gallimore, Emma Jones, Barbara Ecabert, Hans Acha-Orbea, Manfred Kopf

Journal:

European Journal of Immunology

Year:

2001

Language:

english

File:

PDF, 191 KB

english, 2001

9

Depletion of CD25+ regulatory cells uncovers immune responses to shared murine tumor rejection antigens

Denise Golgher, Emma Jones, Fiona Powrie, Tim Elliott, Awen Gallimore

Journal:

European Journal of Immunology

Year:

2002

Language:

english

File:

PDF, 206 KB

english, 2002

10

CD59a deficiency exacerbates influenza-induced lung inflammation through complement-dependent and -independent mechanisms

M. Paula Longhi, Anwen Williams, Matthew Wise, B. Paul Morgan, Awen Gallimore

Journal:

European Journal of Immunology

Year:

2007

Language:

english

File:

PDF, 273 KB

english, 2007

11

Potent T cell agonism mediated by a very rapid TCR/pMHC interaction

Jonathan M. Boulter, Nicole Schmitz, Andrew K. Sewell, Andrew J. Godkin, Martin F. Bachmann, Awen M. Gallimore

Journal:

European Journal of Immunology

Year:

2007

Language:

english

File:

PDF, 276 KB

english, 2007

12

Setting the threshold for extra-thymic differentiation of Foxp3+ Tregs: TGF-β-dependent and T-cell autonomous

Andrew Godkin, Awen Gallimore

Journal:

European Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 83 KB

english, 2011

13

Cytotoxic T cells—protection from disease progression—protection from infection

Frances Gotch, Awen Gallimore, Andrew McMichael

Journal:

Immunology Letters

Year:

1996

Language:

english

File:

PDF, 427 KB

english, 1996

14

Complement: central to innate immunity and bridging to adaptive responses

B. Paul Morgan, Kevin J. Marchbank, M. Paula Longhi, Claire L. Harris, Awen M. Gallimore

Journal:

Immunology Letters

Year:

2005

Language:

english

File:

PDF, 285 KB

english, 2005

15

Limited in vivo reactivity of polyclonal effector cytotoxic T cells towards altered peptide ligands

Patrick Bättig, Philippe Saudan, Tazio Storni, Awen Gallimore, Martin F. Bachmann

Journal:

Microbes and Infection

Year:

2005

Language:

english

File:

PDF, 470 KB

english, 2005

16

CD25+ regulatory T cells and tumor immunity

Emma Jones, Michaela Dahm-Vicker, Denise Golgher, Awen Gallimore

Journal:

Immunology Letters

Year:

2003

Language:

english

File:

PDF, 185 KB

english, 2003

17

Regulation of tumour immunity by CD25+ T cells

Awen Gallimore, Shimon Sakaguchi

Journal:

Year:

2002

Language:

english

File:

PDF, 101 KB

english, 2002

18

The influence of macrophage inflammatory protein-1α on protective immunity mediated by antiviral cytotoxic T cells

Emma Jones, David A. Price, Michaela Dahm-Vicker, Vincenzo Cerundolo, Paul Klenerman, Awen Gallimore

Journal:

Year:

2003

Language:

english

File:

PDF, 187 KB

english, 2003

19

The MHCElocus in macaques is polymorphic and is conserved between macaques and humans

Jonathan E. Boyson, Stephen N. McAdam, Awen Gallimore, Thaddeus G. Golos, Xiaomin Liu, Frances M. Gotch, Austin L. Hughes, David I. Watkins

Journal:

Year:

1995

Language:

english

File:

PDF, 995 KB

english, 1995

20

Regulatory T cells and tumour immunity – observations in mice and men

Awen Gallimore, Andrew Godkin

Journal:

Year:

2008

Language:

english

File:

PDF, 246 KB

english, 2008

21

Novel role of regulatory T cells in limiting early neutrophil responses in skin

Hannah Richards, Anwen Williams, Emma Jones, James Hindley, Andrew Godkin, Anna Katharina Simon, Awen Gallimore

Journal:

Year:

2010

Language:

english

File:

PDF, 909 KB

english, 2010

22

10.1038/ni733

Leung, Ray K. M., Thomson, Kirsty, Gallimore, Awen, Jones, Emma, Van den Broek, Maries, Sierro, Sophie, Alsheikhly, Abdul-Razzak, McMichael, Andrew, Rahemtulla, Amin

Journal:

Nature Immunology

Year:

2001

Language:

english

File:

PDF, 2.09 MB

english, 2001

23

HIV-specific cytotoxic T-cells in HIV-exposed but uninfected Gambian women

Rowland-Jones, Sarah, Sutton, Julian, Ariyoshi, Koya, Dong, Tao, Gotch, Frances, McAdam, Steve, Whitby, Denise, Sabally, Sehu, Gallimore, Awen, Corrah, Tumani

Journal:

Nature Medicine

Year:

1995

File:

PDF, 890 KB

1995

24

Early suppression of SIV replication by CD8+ nef-specific cytotoxic T cells in vaccinated macaques

Gallimore, Awen, Cranage, Martin, Cook, Nicola, Almond, Neil, Bootman, Janet, Ruo, Erling, Silvera, Pete, Dennis, Michael, Corcoran, Terry, Stott, Jim

Journal:

Nature Genetics

Year:

1995

File:

PDF, 656 KB

1995

25

Hierarchies of antigen-specific cytotoxic T-cell responses

Awen Gallimore, Hans Hengartner, Rolf Zinkernagel

Journal:

Immunological Reviews

Year:

1998

Language:

english

File:

PDF, 3.91 MB

english, 1998

26

Regulating the immune response to tumours

Gareth J. Betts, Sarah L. Clarke, Hannah E. Richards, Andrew J. Godkin, Awen M. Gallimore

Journal:

Advanced Drug Delivery Reviews

Year:

2006

Language:

english

File:

PDF, 253 KB

english, 2006

27

Fas ligand breaks tolerance to self-antigens and induces tumor immunity mediated by antibodies

Anna Katharina Simon, Awen Gallimore, Emma Jones, Birgit Sawitzki, Vincenzo Cerundolo, Gavin R Screaton

Journal:

Year:

2002

Language:

english

File:

PDF, 369 KB

english, 2002

28

Rapid early innate control of hepatitis C virus during IFN-α treatment compromises adaptive CD4+T-cell immunity

Tom Pembroke, Ian Rees, Kathleen Gallagher, Emma Jones, Paul Mizen, Timur Navruzov, Andrew Freedman, Ceri Fielding, Ian R. Humphreys, Eddie C. Y. Wang, Awen M. Gallimore, Andrew Godkin

Journal:

European Journal of Immunology

Year:

2012

Language:

english

File:

PDF, 923 KB

english, 2012

29

Holding T cells in check – a new role for complement regulators?

M. Paula Longhi, Claire L. Harris, B. Paul Morgan, Awen Gallimore

Journal:

Trends in Immunology

Year:

2006

Language:

english

File:

PDF, 2.16 MB

english, 2006

30

Influenza-induced immunopathology in Cd59a−/− mice

M. Paula Longhi, Anwen Williams, Matthew Wise, B. Paul Morgan, Awen Gallimore

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 79 KB

english, 2007

31

A shRNA mediated knockdown approach to understand the role of CD59 in regulation of human CD4+ T cells

Baalasubramanian Sivasankar, R. James Matthews, Rossen M. Donev, Katherine Gallagher, Awen M. Gallimore, B. Paul Morgan

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 56 KB

english, 2007

32

The role of complement in 3-methylcholanthrene-induced tumour formation

Rhodri T.O. Turner, Gareth J. Betts, Awen M. Gallimore, Claire L. Harris

Journal:

Molecular Immunology

Year:

2007

Language:

english

File:

PDF, 58 KB

english, 2007

33

CD59 blockade on human CD4+ T cells leads to marked enhancement of antigen-specific responses

Sivasankar Baalasubramanian, Paula Longhi, Kathleen Gallagher, Gareth Betts, B. Paul Morgan, Andrew Godkin, Awen Gallimore

Journal:

Molecular Immunology

Year:

2008

Language:

english

File:

PDF, 69 KB

english, 2008

34

The proteasome inhibitor lactacystin prevents the generation of an endoplasmic reticulum leader—derived T cell epitope

Awen Gallimore, Katrin Schwarz, Maries van den Broek, Hans Hengartner, Marcus Groettrup

Journal:

Molecular Immunology

Year:

1998

Language:

english

File:

PDF, 691 KB

english, 1998

35

OX40-Deficient Mice Are Defective in Th Cell Proliferation but Are Competent in Generating B Cell and CTL Responses after Virus Infection

Manfred Kopf, Christiane Ruedl, Nicole Schmitz, Awen Gallimore, Karin Lefrang, Barbara Ecabert, Bernhard Odermatt, Martin F Bachmann

Journal:

Year:

1999

Language:

english

File:

PDF, 322 KB

english, 1999

36

Epithelial Barriers, Microbiota, and Colorectal Cancer

Gallimore, Awen M., Godkin, Andrew

Journal:

Boston Medical and Surgical Journal

Year:

2013

Language:

english

File:

PDF, 696 KB

english, 2013

37

Complement component C3 promotes T-cell priming and lung migration to control acute influenza virus infection

Kopf, Manfred, Abel, Brian, Gallimore, Awen, Carroll, Michael, Bachmann, Martin F.

Journal:

Nature Medicine

Year:

2002

Language:

english

File:

PDF, 243 KB

english, 2002

38

Complement-induced protection: an explanation for the limitations of cell-based tumour immunotherapies

Kempshall, Emma, Thebault, Simon, Paul Morgan, B, Harris, Claire L, Gallimore, Awen

Journal:

Immunology & Cell Biology

Year:

2012

Language:

english

File:

PDF, 442 KB

english, 2012

39

Neutrophils Recruited by IL-22 in Peripheral Tissues Function as TRAIL-Dependent Antiviral Effectors against MCMV

Stacey, Maria A., Marsden, Morgan, Pham N, Tu Anh, Clare, Simon, Dolton, Garry, Stack, Gabrielle, Jones, Emma, Klenerman, Paul, Gallimore, Awen M., Taylor, Philip R., Snelgrove, Robert J., Lawley, Tre

Journal:

Cell Host & Microbe

Year:

2014

Language:

english

File:

PDF, 2.83 MB

english, 2014

40

Flow cytometry makes all the difference

Pembroke, Tom, Gallimore, Awen, Godkin, Andrew

Journal:

Journal of Hepatology

Year:

2013

Language:

english

File:

PDF, 378 KB

english, 2013

41

T cell subsets and colorectal cancer: Discerning the good from the bad

Scurr, Martin, Gallimore, Awen, Godkin, Andrew

Journal:

Cellular Immunology

Year:

2012

Language:

english

File:

PDF, 275 KB

english, 2012

42

Intrahepatic natural killer cell NKp46 expression drives HCV-associated liver inflammation and viral resistance to treatment with interferon alpha

Pembroke, Tom, Gallimore, Awen, Godkin, Andy

Journal:

Year:

2013

Language:

english

File:

PDF, 41 KB

english, 2013

43

87

Humphreys, Ian R., Stacey, Maria A., Marsden, Morgan, Pham, Tu Anh, Clare, Simon, Dolton, Garry, Stack, Gabrielle, Jones, Emma, Klenerman, Paul, Gallimore, Awen M., Taylor, Philip R., Snelgrove, Rober

Journal:

Year:

2014

Language:

english

File:

PDF, 59 KB

english, 2014

44

Rapid innate control of antigen abrogates adaptive immunity

Pembroke, Thomas P. I., Gallimore, Awen M., Godkin, Andrew

Journal:

Year:

2013

Language:

english

File:

PDF, 284 KB

english, 2013

45

High endothelial venules

Gallimore, Awen, Godkin, Andrew, Ager, Ann

Journal:

Year:

2013

Language:

english

File:

PDF, 361 KB

english, 2013

46

Tracking the kinetics of intrahepatic immune responses by repeated fine needle aspiration of the liver

Pembroke, Tom, Gallimore, Awen, Godkin, Andrew

Journal:

Journal of Immunological Methods

Year:

2015

Language:

english

File:

PDF, 756 KB

english, 2015

47

CD200 Receptor Restriction of Myeloid Cell Responses Antagonizes Antiviral Immunity and Facilitates Cytomegalovirus Persistence within Mucosal Tissue

Stack, Gabrielle, Jones, Emma, Marsden, Morgan, Stacey, Maria A., Snelgrove, Robert J., Lacaze, Paul, Jacques, Laura C., Cuff, Simone M., Stanton, Richard J., Gallimore, Awen M., Hussell, Tracy, Wilki

Journal:

Year:

2015

Language:

english

File:

PDF, 1.24 MB

english, 2015

48

High endothelial venules are rare in colorectal cancers but accumulate in extra-tumoral areas with disease progression

Bento, Diana Costa, Jones, Emma, Junaid, Syed, Tull, Justyna, Williams, Geraint T, Godkin, Andrew, Ager, Ann, Gallimore, Awen

Journal:

Year:

2015

Language:

english

File:

PDF, 607 KB

english, 2015

49

Interleukin-6 Is Crucial for Recall of Influenza-Specific Memory CD4+ T Cells

Longhi, Maria Paula, Wright, Kate, Lauder, Sarah N., Nowell, Mari A., Jones, Gareth W., Godkin, Andrew J., Jones, Simon A., Gallimore, Awen M., Garcia-Sastre, Adolfo

Journal:

Year:

2008

Language:

english

File:

PDF, 278 KB

english, 2008

50

Oncogenic Properties of Apoptotic Tumor Cells in Aggressive B Cell Lymphoma

Ford, Catriona A., Petrova, Sofia, Pound, John D., Voss, Jorine J.L.P., Melville, Lynsey, Paterson, Margaret, Farnworth, Sarah L., Gallimore, Awen M., Cuff, Simone, Wheadon, Helen, Dobbin, Edwina, Ogd

Journal:

Current Biology

Year:

2015

Language:

english

File:

PDF, 3.97 MB

english, 2015